This volume is a collection of original essays dealing with Cartesian themes and problems, especially as these arise in connection with Cartesian natural science and the theory of perception, agency, mentality, divinity, and the passions. It focuses in particular on Desmond Clarke's important contributions to these aspects of Descartes's writings.

Stephen Gaukroger and Catherine Wilson split the volume into four distinct parts; Cartesian Science, Mind and Perception, Actions and Passions, and Cartesian Woman. The contributors are internationally known and respected scholars of 17th century philosophy writing on a number of their favourite Cartesian topics.