This book offers a comprehensive examination of how disinformation strategies are designed and deployed in the digital age, focusing on the powerful role new media plays in shaping public perception and psychological response. By bridging theory and practice, the book provides critical tools for identifying, understanding, and combating the effects of false information in today's communication ecosystem. Structured in two main parts, this book first explores the theoretical and psychological underpinnings of disinformation. It delves into media and communication psychology, the history and anatomy of disinformation and the mechanisms of perception management in digital environments. Drawing from communication theories and psychological models, it explains how new media technologies intersect with human cognition and social behavior to create fertile ground for the spread of manipulative content. The second part focuses on practical responses. It presents evidence-based strategies to combat disinformation, ranging from digital literacy campaigns to institutional policies, algorithmic accountability, and AI-supported fact-checking tools. Through detailed case studies--such as election interference and public health misinformation during the COVID-19 pandemic--the book demonstrates the real-world implications of unchecked disinformation. Uniquely interdisciplinary in scope, the book integrates insights from communication science, psychology, sociology, and digital media studies. It offers a nuanced understanding of the psychological vulnerabilities exploited by disinformation, as well as actionable frameworks for resistance and resilience. This book is essential reading for scholars, media professionals, policy makers, educators, and students in the fields of media studies, communication, psychology, political science, and digital culture. It is also valuable for journalists, educators, and civil society actors who seek to understand the deeper dynamics of misinformation and work toward promoting a more informed and resilient society.